SNAP-8 Structure
- Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
- Formula: C41H70N16O16S
- Molecular weight: 1075.157
SNAP-8 (Acetyl Octapeptide-3) is praised for its potential skincare benefits, particularly its anti-aging properties. Here's a brief overview of the benefits of SNAP-8:
Wrinkle and Fine Line Reduction: SNAP-8 is known for its ability to reduce the appearance of wrinkles and fine lines on the skin. It works by limiting the neurotransmitters that cause muscle contraction, thereby reducing the lines caused by repetitive facial expressions.
Promotes Collagen Synthesis: SNAP-8 can work deep within your skin's layers to promote collagen synthesis, enhancing the overall texture of the skin.
Maintains Youthful Skin: It helps maintain youthful collagen and elastin fibers, contributing to flawless, ageless skin.
Safe Alternative to Botox: SNAP-8 is considered a safer, more economical,gentler, and less invasive alternative to Botulinum Toxin (Botox), as it operates as a safe muscle contraction inhibitor.
Specific Target Areas: It's particularly effective in reducing facial wrinkles, particularly around the eyes and on the forehead, which are a result of repeated facial muscle contractions.
SNAP-8 Forms
SNAP-8 comes in different forms that can be incorporated into various skincare products. Here are a few examples:
Powder Form: SNAP-8 often comes in a powder form that can be dissolved and mixed into serums, lotions, or creams. Skincare manufacturers usually use this form.
Serums: Serums are one of the most common forms of skincare products that incorporate SNAP-8. These are lightweight and penetrate deeply into the skin, delivering the benefits of SNAP-8 efficiently.
Creams and Lotions: SNAP-8 is also found in anti-aging creams and lotions. These are typically thicker than serums and provide a barrier on the skin that helps seal in the SNAP-8, allowing it to work longer.
Eye Creams: Due to its effectiveness on expression lines around the eyes, SNAP-8 is often included in eye creams.
Masks: Some facial masks may also include SNAP-8 as an ingredient, providing a more intensive treatment.
How to Use SNAP-8?
Concentration: For a DIY approach, add 90 drops of SNAP-8 Peptide to a 1-ounce base, custom formula, or existing product for a 10% concentration.
Regular Use: Regular use of SNAP-8 serum can assist in reducing the intensity of facial muscle contractions, limiting the repetitive motions that contribute to the formation of wrinkles.
Application: SNAP-8 peptide is typically found in serums and creams. It is usually applied to the face twice daily, once in the morning and once at night.
Quantity: Apply 1-2 pea-sized amounts of the product on your skin.
Target Areas: Apply a small amount to expression lines around the eyes, frown lines, and around the mouth for best results.
What Is the Science Behind Snap-8 Peptide?
The science behind SNAP-8 revolves around its impact on neurotransmitters and muscle contractions in the face.
Neurotransmitter Inhibition: SNAP-8 works by inhibiting neurotransmitters from sending signals to specific facial muscles. This process is similar to anti-wrinkle injections but is considered a safer and milder alternative.
Collagen Production: When applied topically to the skin, SNAP-8 sends a message to the body to produce collagen. Collagen is a protein that helps maintain skin elasticity and firmness; its production reduces with age.
SNARE Complex Interference: Acetyl Hexapeptide-8, a component of SNAP-8, mimics the N-terminal end of SNAP-25, a protein essential for the successful docking and release of neurotransmitters. It competes with the natural protein for a position in the SNARE complex, which mediates vesicle fusion, leading to muscle relaxation.
Glutamate Release Reduction: Studies show that SNAP-8 can reduce the release of glutamate, a neurotransmitter involved in muscle contraction. This action contributes to its anti-wrinkle effect.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662462/