LL-37 (CAP-18) 10mg

What Is LL-37 And What Is Its Mechanism Of Action?

As we already said, LL-37 belongs to the antimicrobial peptides group, which further branches out to cathelicidins and defensins. Though both subfamilies are a part of our innate immune system, in our body there are many classes of defensins but only one of cathelicidins. This is the group LL-37 falls into.

This is why LL-37 is of such interest to scientists, as a novel peptide and a superior alternative to the ineffective antibiotics.

And how does LL-37 work? - A lot of its potency comes from the fact it can penetrate (as well as damage) a pathogen's membrane, making the pathogen itself more vulnerable and susceptible to damage.

An important thing to note about cationic peptides is that they do not act on a healthy host cell membrane; they are “drawn” to the negatively charged lipid membranes of intruder microorganisms, allowing for a pinpoint precision and neutralization.

Brand:	PeptideShop
Action:	LL-37 is a human antimicrobial peptide that consists of 12-100 amino acids, whose primary role is to kill bacteria via the membrane interactions.
Sequence:	-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
Molecular Formula:	C205H340N60O53
Molecular Weight:	4493.342 g/mol
PubChem CID:	16198951
CAS Number:	154947-66-7
Synonyms:	CAP-18, Cathelicidin, antibacterial peptide LL-37
Purity:	99%
Origin:	United States
Size:	10g
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